Weekly HFMD cases hit record high this year (Singapore)

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The Straits News https://www.straitstimes.com/singapore/weekly-hfmd-cases-hit-record-high-this-year

PUBLISHED

AUG 16, 2018, 5:00 AM SGT

1,249 cases reported from July 29 to Aug 4; pre-schools told to take preventive measures

The weekly number of cases of hand, foot and mouth disease (HFMD) here has climbed to a record high this year, along with slightly more cases from the strain that caused the death of two children in Malaysia recently.

The 1,249 cases of HFMD reported in Singapore between July 29 and Aug 4 – the latest publicly available statistics as of yesterday – are the highest number reported in a week this year.

It is also almost 1 1/2 times the 868 cases reported at the same time last year.

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New test promises to pick up HFMD cases before symptoms show (Singapore)

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The Straits News https://www.straitstimes.com/singapore/new-test-promises-to-pick-up-hfmd-cases-before-symptoms-show

PUBLISHED

AUG 21, 2018, 6:59 PM SGT

SINGAPORE – Scientists from the National University of Singapore (NUS) have found a way to identify children with hand, foot and mouth disease (HFMD) from just a few drops of saliva, even before symptoms show.

They hope to eventually make HFMD test kits commonplace in pre-schools and childcare centres so cases can be picked up early to prevent the disease from spreading.

They will first have to test the kits on a larger group of children and get approval from the Health Sciences Authority for their use here.

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Hand foot mouth disease in children (Vietnam)

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Sourced from Vietnam News https://vietnamnews.vn/life-style/463227/hand-foot-mouth-disease-in-children.html#0KT6eiujs0JWPISj.97

Viet Nam NewsBy Dr Nguyễn Trung Hà*

What is it?

Hand Foot Mouth Disease (HFMD) is a highly contagious infectious disease caused by Coxsackie virus (A16) and Enterovirus 71 (EV71). In Việt Nam, HFMD occurs throughout the year, but the peak season is from March until May and September to December. Children can get HFMD at all ages but children below 3 years are more susceptible, as they have not developed immunity against the virus.

Is HFMD the same disease as foot-and-mouth disease in animals?

Despite similar names, these two diseases are completely unrelated and caused by different viruses. Humans cannot get the animal disease and animals cannot get HFMD.

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Hand, foot and mouth disease on rise in Beijing

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Sourced from http://www.xinhuanet.com/english/2018-04/26/c_137138574.htm

BEIJING, April 26 (Xinhua) — More than 140,000 people have been infected with hand, foot and mouth disease (HFMD) and six died from the disease in China this year, according to China’s Center for Disease Control and Prevention (CDC).

As of April 20, a total of 141,978 cases had been reported, with six deaths and 581 in critical conditions. The disease incidence rate was lower than the same period of last year, the CDC said in a statement.

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Hand, foot and mouth disease kills 6 in China

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Sourced from http://www.xinhuanet.com/english/2018-04/26/c_137138574.htm

BEIJING, April 26 (Xinhua) — More than 140,000 people have been infected with hand, foot and mouth disease (HFMD) and six died from the disease in China this year, according to China’s Center for Disease Control and Prevention (CDC).

As of April 20, a total of 141,978 cases had been reported, with six deaths and 581 in critical conditions. The disease incidence rate was lower than the same period of last year, the CDC said in a statement.

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Lecture Video: 2018 Workshop on Regulation of Enterovirus Vaccines in Taiwan and Vietnam

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Date: March 6, 2018

Location: Taipei, Taiwan

20180306

Time Opening Remark
09:00-09:05 Dr. Tzou-Yien Lin Chair person, Board of Directors, NHRI, Taiwan
I. Taiwan Regulation Section
Topic Speaker Moderator
09:05-09:30 Development of Enterovirus71 (EV71) Vaccines in Taiwan Dr. Min-Shi Lee
NHRI, Taiwan		 Dr. Mei-Shang Ho
Academia SINICA, Taiwan
09:30-10:00 Clinical Perspective on EV 71 Vaccines Regulation in Taiwan Dr. Ya-Lei Wang
CDE, Taiwan
10:00-10:30 CMC Perspective on EV 71 Vaccines Regulation in Taiwan Dr. Yu-Ping Ho
CDE, Taiwan
10:45-11:15 Lot Release System for Vaccines in Taiwan Dr. Yi-Chen Yang
FDA, MOHW, Taiwan
11:15-11:40 Current Status and Future Plans for Clinical Trial of EV 71 Vaccines (Enimmune) Dr. Chin-Fen Yang
Enimmune, Taiwan
11:45-12:15 Current Status and Future Plans for Clinical Trial of EV 71 Vaccines (Medigen) Dr. Kathy Tai
Medigen Vaccines, Taiwan
II. Vietnam Regulation Section
13:30-14:00 Review on IND of Human Vaccines in Vietnam Dr. Nguyen Ngo Quang
ASTT, MOH,
Vietnam		 Prof. Oliver Yoa-Pu Hu
Taipei Medical University, Taiwan
14:00-14:30 Regulati on on Surveillance of Adverse Event Following Immunization Dr. Nguyen Minh Hang
GDPM, MOH,
Vietnam
14:30-15:00 Implementation of Vaccine Trials in Vietnam, Experiences from the Pasteur Institute Ho Chi Minh City Dr. Nguyen Vu Thuong
Paster Institute-HCMC,
Vietnam
15:15-15:45 Experiences Sharingon Multi-national Clinical Trials of Pediatric Vaccines in Vietnam Dr. Nguyen Trong Toan
Paster Institute-HCMC,
Vietnam		 Dr. Min-Shi Lee
NHRI, Taiwan
15:45-16:15 Cost of Illness of HFMD in Vietnam Dr. Le Nguyen Thanh Nhan
Children’s Hospital 1,
HCMC, Vietnam
16:15-16:45 Experiences sharing on clinical trials of pediatric vaccines in Vietnam Dr. Do Tuan Dat
VABIOTECH Vaccine,
Vietnam

Lecture Video: 2017 International Workshop on Enterovirus Surveillance and Vaccine Development

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Enteroviruses : Frequently Asked Questions?

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Data from Division of Acute Infectious Diseases, CDC, Taiwan

FAQ

  1. What are enteroviruses?

Enterovirus is a general term of a group of small RNA viruses which accounts for more than 70 viruses, including Coxsackieviruses A, Coxsackieviruses B, polioviruses, echoviruses, and enteroviruses.

  1. Can these enteroviruses only be found in Taiwan?

What are the epidemic seasons?

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Enterovirus / Enterovirus Infection with Severe Complications in Taiwan

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Data from Division of Acute Infectious Diseases, CDC, Taiwan

Background

Enterovirus belongs to a group of small RNA viruses, including polioviruses, Coxsackie A viruses, Coxsackie B viruses, echoviruses, and other enteroviruses (EVD68~). EVA71 has a significantly higher pathogenicity compared to other known enteroviruses, especially regarding neurological complications. Enteroviruses are found in the gastrointestinal tract (the stool of infected persons, mouth) and respiratory tract (such as saliva, sputum, or nasal mucus). Infections can be produced by direct contact with the secretions of infected persons or with contaminated surfaces or objects. Humans appear to be the only known host and source for enteroviruses transmission. The patient is contagious before their onset, and the infectivity will last for weeks after the patient is recovered. There are currently no preventive vaccines for non-polio enteroviruses in Taiwan and no known highly efficacious medicine to eliminate the virus once it is inside the human body. Therefore, enteroviruses will continue to pose a threat to human health for the foreseeable future.

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