Establishment of Asia-Pacific Network for Enterovirus Surveillance

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Conference Report

Mu-Lin Chiu, Shu-Ting Luo, Ya-Yen Chen, Wan Yu Chung, Veasna Duong, Philippe Dussart, Yoke-Fun Chan, David Perera, Mong How Ooi, Nguyen Thi Thanh Thao, Huu Khanh Truong, Min-Shi Lee

Abstract 

Enteroviruses (EV), the major pathogens of hand, foot, and mouth disease (HFMD) and herpangina, affectmillions of children each year. Most human enteroviruses cause self-limited infections except polio-viruses, enterovirus A71 (EV-A71), enterovirus D68 (EV-D68), and several echoviruses (Echo) and cox-sackieviruses (CV). Especially, EV-A71 has repeatedly caused large-scale outbreaks in the Asia-Pacificregion since 1997. Some Asian countries have experienced cyclical outbreaks of severe EV-A71 infectionsand initiated development of EV-A71 vaccines. Five EV-A71 vaccine candidates have been clinically eval-uated and three of them were approved for marketing in China.